| Team name | Location | League | Level | Status |
|---|---|---|---|---|
| Frederick Keys | Frederick, Maryland | MLB Draft League | professional | defunct |
| Mahoning Valley Scrappers | Niles, Ohio | MLB Draft League | professional | active |
| State College Spikes | State College, Pennsylvania | MLB Draft League | professional | active |
| Trenton Thunder | Trenton, New Jersey | MLB Draft League | professional | active |
| West Virginia Black Bears | Morgantown, West Virginia | MLB Draft League | professional | active |
| Williamsport Crosscutters | Williamsport, Pennsylvania | MLB Draft League | professional | active |